International Standard
ISO 23970:2021
Milk, milk products and infant formula — Determination of melamine and cyanuric acid by liquid chromatography and tandem mass spectrometry (LC-MS/MS)
Reference number
ISO 23970:2021
Edition 1
International Standard
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ISO 23970:2021
Published (Edition 1, 2021)

ISO 23970:2021

ISO 23970:2021
CHF 96
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This document specifies a method for the determination of melamine and cyanuric acid with liquid chromatography in combination with tandem mass spectrometry (LC-MS/MS). The method has been validated in an interlaboratory study via the analysis of spiked samples of milk-based infant formula, soy-based infant formula, milk powder, whole milk, soy drink and milk chocolate ranging from 0,71 mg/kg to 1,43 mg/kg for melamine and 0,57 mg/kg to 1,45 mg/kg for cyanuric acid. The limits of quantification (LOQ) for melamine and cyanuric acid in food are 0,05 mg/kg and 0,25 mg/kg, respectively. The upper limit of the working range is up to 10 mg/kg for melamine and up to 25 mg/kg for cyanuric acid.

General information

  •  : Published
     : 2021-09
    : International Standard published [60.60]
  •  : 1
     : 18
  • ISO/TC 34/SC 5
  • RSS updates

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