Abstract

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This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of mainstream cigarette smoke by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).


General information 

  • Status
     : Published
    Publication date
     : 2021-02
  • Edition
     : 2
    Number of pages
     : 14
  • Technical Committee
     : ISO/TC 126 Tobacco and tobacco products
  • ICS
     :
    65.160 Tobacco, tobacco products and related equipment

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