Reference number
ISO 19290:2021
© ISO 2025
International Standard
ISO 19290:2021
Cigarettes — Determination of tobacco specific nitrosamines in mainstream cigarette smoke — Method using LC-MS/MS
Edition 2
2021-02
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Published (Edition 2, 2021)

ISO 19290:2021

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Format
CHF 98
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Abstract

This document specifies a method for the quantification of four tobacco specific nitrosamines (TSNAs) in the total particulate matter of mainstream cigarette smoke by using reversed phase high performance liquid chromatography with tandem mass spectrometry (LC-MS/MS). The quantified TSNAs are: N-nitrosonornicotine (NNN), N-nitrosoanatabine (NAT), N-nitrosoanabasine (NAB) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).

General information

  • Status
     : Published
    Publication date
     : 2021-02
    Stage
    : International Standard published [60.60]
  • Edition
     : 2
    Number of pages
     : 14
  • Technical Committee :
    ISO/TC 126
    ICS :
    65.160 
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